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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354e466658e8f5799c0c2cbbd100e8ee0ef786aac38afba51485f9bff5a92411' 
  AND token = '8Qjt5caRoZBmAj2+/yvWPGcir2vtqY6NXycq4WT7cLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}