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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a2165c05841ca91072a50bf787b4d749620dadbf6a9875bed83a1226beda018' 
  AND token = 'iPG17qM4qF+oHA8IZ90cAy6mn3z4kIZ/ffQbZNuosFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}