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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '590b23ecef1bf89ee3a1ca20c1dbf24773a1c44b0046d55ebb21207e7a7a1568' 
  AND token = 'p8sjkHl7uxFh8XFqrB+syWIgR/AYmA/MU1Xfdg5e4jU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}