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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '667420090fe5a09b2d158e39b08d3c3c91674e257ad69169000c5a643f0c97e9' 
  AND token = 'V2O9Pvd0b01byB/bzEWSjjrOPMi6juVF5Ix00ja7XWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}