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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a818d5c0cfb065dcae3508b467bfc8661ce9a664bde5c838c4cb6c7dae1931b9' 
  AND token = 'hE0XoO1p3kvbN41pSr+TKfqYlzkj1lmPWmQs3OqE16o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}