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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48b3f43f7708b4157d6b8874745e30393ebee4d4f7ad2522a7631c5350e3d36f' 
  AND token = 'DEDBq2JxmVpzzqatjs5taqI1m0XA13Evvs14FObKZMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}