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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c7b40257b69b344f5ffca5a1603bba310c167949da9b2c9b8aaeec453afafec' 
  AND token = 'mp66H/h/6+sCHbt1fckzb5UhUWY2BCt+Rl1d6RMRWw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}