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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b521bb4133512a43397c7452080ccbb3dd1ee8fccbc69cf3ee0db78911c5f3c' 
  AND token = 'Oa6siuuEdk0VeM8xr936VEAeDDTeW88u4Rqjg8FfEHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}