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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7ad959ca06584d5630d64c747dcd7ba0b63d2e4c78352236c3a9f65eac881c5' 
  AND token = '21t1d8WILU4ZSIjeu3ZVNiUFf3ve4r9EZOW8INecWj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}