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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0c889882b25640712b4c7e94f92dda4f0ead77de4b07de19c3b6b8f1bae21e6' 
  AND token = '8KpRyVNsqDRydVous120D/65x6kBCFj0fvbqmm2r5UA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}