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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e6ba494c430bcbf5934796eb4e9c62aab90cfd75f64ad95562b49c24c2f1cc' 
  AND token = '/EUzn6ZLjAcY4sv7bjtUHgewZy837CeWa6ZuhS+ioaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}