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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bedb2c4f93d6e8fec5555b67f16c633267c108e16c15f7b2fbc75fd3266b3a7' 
  AND token = 'afB7u+xCsDg3xD8+Xm2onpK5pO0bF2uYHe/bghFIEdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}