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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '224ed752cfd0f73598b4dc89d467bbc7357d2fc01350a96986fd17a9844734e9' 
  AND token = '8uXPXp5T2wwb+7Mkp/XsRNcSGzU8CqyT2/15d7GW8wY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}