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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9227a893bc2fa4c0d58496de4a5f427f7155d22249bfeec4f4166bed880dceb3' 
  AND token = 'lzBxBkWJTGD7V8taj8LvfPVVeYQ8V339kZScsGUoHMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}