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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '465aa1c791ea6cf7b5c72566a95cd4bc4a1a003b51554bf18b206c7788d50cee' 
  AND token = 'bR7ILs4/d8WUHBnIDmWDRxmePvnOcLlBhQKA1NUuLsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}