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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b398f142abe667ccfa513dd02f7be1fd394d0b05ac37d20ef792d71b0c68fb5a' 
  AND token = 'A3REZqG7DsmqxqYAxFhUrvqM9jO5SnELYeO2Gym12bA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}