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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2653894f9c99b2e531b41ccdd25764224d6a50986cb2c6ddd21558a1683e66c3' 
  AND token = 'akMY2cKypt0H9veI0lOxdOxT8A0hSVKgAUMCLYTLti4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}