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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e13411aa986d0fdee910d55717b25a488585ff159f71b35d10e6456b1a5f0e43' 
  AND token = '1QNK2M9uW8e36hedYaB2+1Cps/UoSJv7Vo0+FvsJvis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}