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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61849a9bacc50612ac7f3703ae7c0d30059982dd3dc839b51b9239d55930037f' 
  AND token = 'GrckXuGFC3uhDHZfnpEfzwYYDuqDa3R+4uXp37LrrvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}