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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd58aa86dc330c81b67638c033466c4f7268351ac11d66fce96226b4e2f7be209' 
  AND token = 'DaqnS9PQEVtnp2LqYhyfT4TSMd5RfpsdxsrcfwD1FwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}