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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7c2051634a778c2c3420eb5804c244f9507b802b07376c6bff723b1cc0d5149' 
  AND token = 'mDB+vObnT1YjjQI/9gDWkBP83z3jJmops4r/0/JrR18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}