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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c95368f38f8f32e0401488bea4765ff79eda5260fc018c3fd3cf446407814d54' 
  AND token = 'jlW7Jp0e8Uo5iXS0YpPOC2hVQXjFDJ/H5E4GNaVWUTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}