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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b728d0494e1bf8611b72a1471d77efd506a6a02a8e216f79273a3896dfc3c211' 
  AND token = 'jEgVjoQHailcf8QkOL7j99u8UXP0QiPpqDEKU8cCrIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}