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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd4a78f88efc92ad48c146b711816c8adee9499c7d9f49e94f1912b5d54795f6' 
  AND token = 'JRFvsR1ntla9gf2XHlYdlnMiLcJWWKjz25gwIXHJK/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}