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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '98cb22a3a80a8eb5be03e8aff1fa0467cc47abc6cb2a1453b1c7c20c04567f08' 
  AND token = 'EboEZ7hDYY+4YribqnGOCzBTZNMZgweGgeCWLc8cFUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}