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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '993df5d8db9bc7af3c226b9bf03df9b88e99b5cced4d180cac99f4cc1bdcbe29' 
  AND token = '2Wsm1s7pKlZ6gwQGoe7E//MHQHil7nRWLYWJ3JDmaro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}