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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15a501dcbabeb4b2f9b7f7af02af7eec66d2f3053b5952dfd53af7c6d71d1b59' 
  AND token = '9/x4t4MdVLUuYE5w79GaeeM+TKRg+oY2K3+tac0N9GI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}