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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dc91423532110d8d9e76c8048862da3d6bc729d258205e5adb971620c05f7c7' 
  AND token = 'fMsCWcfFYRiH3cNXCNz7D06o4/NO3dWqV+ttF8uWUpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}