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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f43050e262a9a66dd72d85e3a8c6645e38e768d9a392d32831b63ad0e5f9a9da' 
  AND token = 'TUI/g72b0CmpslbqHmQSIHf4ZiCrYYVdcpuEKA6ETEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}