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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf6bad2cd41e9cf73c7604f38cfd184ce4af54d2687fa9d3e8a6de44cb6d00a0' 
  AND token = '+gdIe70U6EP5Hb06cf/GonuOsF7uisXE5htOP2+J7U4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}