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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1774c93718ba906175a1a68150f2d3aec5c50f80ef4debb6febb5a6eee5f0787' 
  AND token = 'ltygGfHVUBZikolWB/T3Txu6Hh8iPSSwYCcyKir+0hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}