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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aee75060fd82f5ee92cd3be89715e23f5a691d019eba18a9646a7edc25e05a22' 
  AND token = 'qOnJdtTgNFfCxl0Wrclwkcr9KdW2pBoPlVLK47NisRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}