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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06cd3660084f5daf8aca119c6c42efa468e66622f0026cb18274d23d17180bce' 
  AND token = 'NrnSNndJRz9RMRwCvOcnrX73n+l6dBGa8j6LUu2WMAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}