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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1655e2cad104f44d943c8b13fc724b9a8ef9932f93d12e886e07b14a4d0f42a4' 
  AND token = 'qsih96kBfe046xDWCZU+ZsNqr6oD6v0B8mwceJiIRg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}