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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e104ebe24512b3075b6cfb278ed466e3fb5d3ddd87e14404ed3965a0691e2bed' 
  AND token = 'rz1qDLam6tOVejQuCs//vU21wISoXm2qWrCqImpr7Ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}