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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f38322f4a25d4180e68ea5e04dbb5183895959d071a7f37e77878c56a9f75a97' 
  AND token = 'Up9vdthC5enHmwdXH/EolTMeILQaGQd2hhp6KyI95HQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}