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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55e49ed6a26415714083d8131ea6a715cce97ffb83a57f45bf3ccbfee8d145d4' 
  AND token = 'oQ1FE+w7eMDUSfSAhf/TNHhcyOUasBvgFVZeMuk4Znc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}