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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ef4d133ece1e9e1fae635e7bee873e2b8adca7f45cd5a7f279a1eaab53c003d' 
  AND token = 'PGi9A8+FaRAsWMkXZ8nmR92tbjBrgP4cmwrKcL3o3TI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}