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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dfb0d15c1afa7bfff3819ba0183da2901b381b2b1ce5fea199dbc4d9cc6c488' 
  AND token = 'EHc9xuhMUG+Dz5S2GpdqP13zlg6/Snhor5llEkBEV98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}