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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '256e11c86785a561dacb3d345e8ef4077a6204cfed3ef090c1cca54def0b539a' 
  AND token = '7oRt25MaD5dGFWzvW/eAaEv4OutpVR7LnDCtQjxM6gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}