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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b873476d36c3660b3d1210ca9e34df2f189b04331e3386b7f463e6de34c770c' 
  AND token = 'BHs+15+mjyZQxYKxxLpa4AV4ibh/fo7wxBY3FXxasYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}