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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25dc25395d546d082e4127d4f8f515e10ad8e60d3d77c18742aaa768ac05713d' 
  AND token = 'rq7rZZ1dtvIKow0/scy225rTpj+RiQu5tzNNRhw5gZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}