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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a53bd35a9c32464533a47c17f2990d47a48e80337f52777aff051d9353d66d2' 
  AND token = 'ZHlPc4Uldf21n3mFdA3SeiWlEGm1b6SlGn2lDcJU7tE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}