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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88ea64828290bd09e15585b07b594635f5f809a6619b3a8151bf7d14df417c6e' 
  AND token = 'xpJ57BeaO+nthOyaMyBMAnFDIDVMYqifmwa6TpnV1h8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}