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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f336080ff546b5363aaf29598079bb9d41e3b8ebbf2cf73eb4e12a64e16b706' 
  AND token = 'LYYSDdIvIL9qCM4DrcAk2xrIJM1/Ip/lvbleS+cCSs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}