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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5b207ba4b6320f18dc36f25fc094ff70b5febc72cb0042c6b1190f597b6c86f' 
  AND token = 'jJvGeXEAGIXeLJo4RRo6rPMc9CunbL/dwR5+UZiPEDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}