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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b49774a4b5a3dbce08c61544e5449511d205326f97e8b058cc27dbd1d459645' 
  AND token = '6DxPNoJNEVf+v8J/oRNmDqiEfJTwNyDu/M6w+U6Y7wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}