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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59c62e8b74d399a0ccdff601340a5b382127ae1ab6ddb40d8fcff40a222daa3d' 
  AND token = '4RO/1bVr8n37PCOZX5RgaXy+j4wib8tyV9XZGs/+5lY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}