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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d50658872b09023667cb6f6a08eece85248ec8f3c5e1c9c97799f25824a31bb' 
  AND token = 'P8zY8WYRWLgoH3m0iOY93RP/nlNI4QyNITJQKuhz3fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}