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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f91bcc29e924581fecd10bc8188a42e733923bee1b6faed1d306a61a3d22b3b3' 
  AND token = 'ONj4aBmS0q7aeeykhwnegCajt24s0aYVEAQhRdW8S7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}